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- $Unique_ID{BRK03208}
- $Pretitle{}
- $Title{lorazepam}
- $Subject{Ativan Wyeth Benzodiazepine sedative/hypnotic lorazepam anxiety
- depression depressant central nervous system brain spinal cord nervousness}
- $Volume{}
- $Log{
- Ativan 0.5 mg*0320801.scf
- Ativan 1 mg*0320802.scf
- Ativan 2 mg*0320803.scf}
-
- Copyright (C) 1993 Publications International, Ltd.
-
-
- lorazepam
- ------------------------------------------------------------------------------
-
- BRAND NAMES (Manufacturers)
-
- Ativan (Wyeth)
- lorazepam (various manufacturers)
-
- TYPE OF DRUG
-
- Benzodiazepine sedative/hypnotic
-
- INGREDIENT
-
- lorazepam
-
- DOSAGE FORM
-
- Tablets (0.5 mg, 1 mg, and 2 mg)
-
- STORAGE
-
- This medication should be stored at room temperature in a tightly closed,
- light-resistant container.
-
- USES
-
- Lorazepam is prescribed to treat symptoms of anxiety and anxiety
- associated with depression. It is not clear exactly how this medicine works,
- but it may relieve anxiety by acting as a depressant of the central nervous
- system (brain and spinal cord). This medication is currently used by many
- people to relieve nervousness. It is effective for this purpose for short
- periods, but it is important to try to remove the cause of the anxiety as
- well.
-
- TREATMENT
-
- Lorazepam should be taken exactly as your doctor directs. It can be
- taken with food or a full glass of water if stomach upset occurs. Do not take
- this medication with a dose of antacids, since they may slow its absorption
- from the gastrointestinal tract.
- If you are taking this medication regularly and you miss a dose, take the
- missed dose immediately if you remember within an hour. If more than an hour
- has passed, skip the dose you missed and wait for the next scheduled dose. Do
- not double the dose.
-
- SIDE EFFECTS
-
- Minor.
-
- Bitter taste in the mouth, constipation, diarrhea, dizziness, drowsiness
- (after a night's sleep), dry mouth, fatigue, flushing, headache, heartburn,
- excessive salivation, loss of appetite, nausea, nervousness, sweating, or
- vomiting. As your body adjusts to the medication, these side effects should
- disappear.
- To relieve constipation, increase the amount of fiber in your diet (fresh
- fruits and vegetables, salads, bran, and whole-grain breads), exercise, and
- drink more water (unless your doctor directs you to do otherwise).
- Dry mouth can be relieved by chewing sugarless gum or by sucking on ice
- chips.
- If you feel dizzy, sit or lie down for a while; get up slowly from a
- sitting or reclining position, and be careful on stairs.
-
- Major.
-
- Tell your doctor about any side effects that are persistent or
- particularly bothersome. IT IS ESPECIALLY IMPORTANT TO TELL YOUR DOCTOR about
- blurred or double vision, chest pain, depression, difficulty in urinating,
- fainting, falling, fever, joint pain, hallucinations, memory problems, mouth
- sores, nightmares, palpitations, rash, shortness of breath, slurred speech,
- sore throat, uncoordinated movements, unusual excitement, unusual tiredness,
- or yellowing of the eyes or skin.
-
- INTERACTIONS
-
- Lorazepam interacts with several other types of medications:
- 1. To prevent oversedation, this drug should not be taken with alcohol,
- other sedative drugs, or central nervous system depressants (such as
- antihistamines, barbiturates, muscle relaxants, pain medicines, narcotics,
- medicines for seizures, and phenothiazine tranquilizers) or with
- antidepressants.
- 2. This medication may decrease the effectiveness of carbamazepine,
- levodopa, and oral anticoagulants (blood thinners) and may increase the
- effects of phenytoin.
- 3. Disulfiram, cimetidine, and isoniazid can increase the blood levels of
- lorazepam, which can lead to toxic effects.
- 4. Concurrent use of rifampin may decrease the effectiveness of
- lorazepam.
- BE SURE TO TELL YOUR DOCTOR about any medications you are currently
- taking, especially any listed above.
-
- WARNINGS
-
- * Tell your doctor about unusual or allergic reactions you have had to
- any medications, especially to lorazepam or other benzodiazepine tranquilizers
- (such as alprazolam, chlordiazepoxide, clorazepate, diazepam, flurazepam,
- halazepam, midazolam, oxazepam, prazepam, temazepam, and triazolam).
- * Tell your doctor if you now have or if you have ever had liver disease,
- kidney disease, epilepsy, lung disease, myasthenia gravis, porphyria, mental
- depression, or mental illness.
- * This medicine can cause drowsiness. Avoid tasks that require
- alertness, such as driving a car or using potentially dangerous machinery.
- * This medication has the potential for abuse and must be used with
- caution. Tolerance may develop quickly; do not increase the dosage without
- first consulting your doctor. It is also important not to stop this drug
- suddenly if you have been taking it in large amounts or if you have used it
- for several weeks. Your doctor may want to reduce the dosage gradually.
- * This is a safe drug when used properly. When it is combined with other
- sedative drugs or alcohol, however, serious side effects can develop.
- * Be sure to tell your doctor if you are pregnant. This medicine may
- increase the chance of birth defects if it is taken during the first three
- months of pregnancy. In addition, too much use of this medicine during the
- last six months of pregnancy may cause the fetus to become dependent on it,
- resulting in withdrawal side effects in the newborn. Also, use of this drug
- during the last weeks of pregnancy may cause drowsiness, slowed heartbeat, and
- breathing difficulties in the newborn. Tell your doctor if you are
- breast-feeding. This drug can pass into the breast milk and cause drowsiness,
- slowed heartbeat, and breathing difficulties in the nursing infant.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-